While running a search for 'city simulation' for an up coming conference presentation I came across a movie of the Playstation 2 game 'Tokyo Bus Guide 2'. Not available outside of the Japan, for obvious reasons, the game nevertheless displays an interesting way to view a virtual model of the city.
The majority of real cities in games are based around street car racing and as such it is difficult to appreciate the modelling behind the simulation. In a bus based game the pace is slower so it is easier to view how the city was constructed.
If they were to make a London version they would have to include a 'hoodie' with his/her mobile phone on 'speaker' mode playing 'Urbanz Diss' on the 168 to Camden Town.